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Basic Information |
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Product Name |
Minoxidil |
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Appearance |
White powder |
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CAS No |
38304-91-5 |
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Specification |
99% |
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Test Method |
HPLC |
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EINECS |
253-874-2 |
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Molecular Formula |
C9H15N5O |
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Molecular Weight |
209.25 |
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Loss on Drying |
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≤0.5% |
Minoxidil was the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). Before that, minoxidil had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure, with side effects that included hair growth and reversal of male baldness. In the 1980s, UpJohn Corporation came out with a topical solution of 2% minoxidil, called Rogaine, for the specific treatment of androgenetic alopecia. Since the 1990s, numerous generic forms of minoxidil have become available to treat hair loss while the oral form is still used to treat high blood pressure.
The popularity hair loss treatment is due to the general preference in the overall population for the cosmetic appearance of a full head of hair. Minoxidil is used to stimulate hair growth in areas of the scalp that have stopped growing hair. As of early 2001, the exact mechanism of action of minoxidil is not known.
Minoxidil is currently the world's only significant effect hair loss topical chemical drugs . This medicine is used to lower blood pressure orally . If an external high doses , the drug will be absorbed into the body through the skin , may cause headache, hypotension. If you accidentally dropped his face , may cause the drop of the Department overgrown hairs . But it is precisely because " Minoxidil " is currently the world's only significant effect hair loss topical chemical drugs.
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Items |
Standards |
Results |
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Physical Analysis |
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Description |
White Powder | Complies |
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Assay |
99%(HPLC) | 99.2% |
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Mesh Size |
100 % pass 80 mesh | Complies |
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Ash |
≤ 5.0% | 2.85% |
| Loss on Drying | ≤ 5.0% | 2.85% |
| Chemical Analysis | ||
| Heavy Metal | ≤ 10.0 mg/kg | Complies |
| Pb | ≤ 2.0 mg/kg | Complies |
| As | ≤ 1.0 mg/kg | Complies |
| Hg | ≤ 0.1 mg/kg | Complies |
| Microbiological Analysis | ||
| Residue of Pesticide | Negative | Negative |
| Total Plate Count | ≤ 1000cfu/g | Complies |
| Yeast&Mold | ≤ 100cfu/g | Complies |
| E.coil | Negative | Negative |
| Salmonella | Negative | Negative |
1. Minoxidil powder needs to be applied once or twice daily for hair to be maintained.
2. For maximum effect, the solution should be in contact with the scalp for hours before being washed out. It does not seem capable of reducing DHT or the enzyme responsible for its accumulation around the hair follicle, 5-aliha reductase, which are the main causes of male pattern baldness in genetically susceptible individuals. Therefore, when treatment is stopped, the DHT already accumlated around the follicle has its expected effect, and the follicle usually shrinks again and eventually dies.
3. Minoxidil powder can promote hair regrowth,slow or stop hair loss and treat high blood pressure.
Application of Minoxidil Sulphate
(1)Promote hair regrowth.
(2)Slow or stop hair loss.
(3)Treat high blood pressure.
