Huperzine A is extracted from Huperzia serrata. It is a reversible acetylcholinesterase inhibitor and NMDA receptor antagonist that crosses the blood-brain barrier.The structure of the complex of huperzine A with acetylcholinesterase has been determined by X-ray crystallography.
For some years, huperzine A has been investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease.A 2013 meta-analysis found that huperzine A may be efficacious in improving cognitive function, global clinical status, and activities of daily living for individuals with Alzheimer’s disease. However, due to the poor size and quality of the clinical trials reviewed, huperzine A should not be recommended as a treatment for Alzheimer’s disease until further high quality studies confirm its beneficial effects.
Huperzine A is also marketed as a dietary supplement with claims made for its ability to improve memory and mental function.Huperzine A has also been postulated as a potential treatment formyasthenia gravis.
Specification:
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Test Method: |
HPLC |
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CAS NO.: |
120786-18-7 |
Country of Origin: |
China |
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Part Used: |
Leaf |
Type of extraction: |
Alcohol&Water |
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ANALYSIS |
SPECIFICATION |
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Appearance |
Brown Fine Powder |
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Assay(Huperzine A) by HPLC |
≥1.0% |
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Odor |
Characteristic |
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Sieve analysis |
100% pass 80 mesh |
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Loss on Drying |
≤5% |
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Moisture |
≤2% |
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Heavy Metal |
<10ppm |
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As |
<2.0mg/kg |
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Ge |
<0.3mg/kg |
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Pb |
<5.0mg/kg |
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Hg |
<0.2mg/kg |
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Microbiology |
|
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Total Plate Count |
<1000cfu/g |
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Yeast & Mold |
<100cfu/g |
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E.Coli |
Negative |
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Salmonella |
Negative |
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Conclusion |
Conform with specification |
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Storage |
Store in sealed containers at cool & dry place. |
|
|
Protect from light, moisture and pest infestation. |
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Shelf life |
2 years when properly stored |
Huperzine A has been proven superior to drugs licensed for the treatment of Alzheimer’s, including the leading anticholine sterase drugs physostigmine and tacrine. Huperzine A improved learning and memory in mice better than tacrine. Unlike physostigmine and tacrine, Huperzine A acts specifically on AchE in the brain rather than AchE found elsewhere in the body i.e., far less is wasted on irrelevant effects. Unlike physostigmine and tacrine, Huperzine A does not appear to bind to receptors in the central nervous system, which can cause adverse side effects. Its effects last 10 to 12 times longer than physostigmine and tacrine (up to 8 hours).
1.Huperzine A can improve memory, thinking, and behavioral function in people;
2.Huperzine A as a treatment of myasthenia gravis effective drugs, better than new Ming;
3.Huperzine A may also protect neurons from cell death caused by toxic levels of glutamate;
4.Huperzine A used as raw materials can be made of alzheimer's disease prevention and health food;
5.Huperzine A is also the treatment of AD in a randomized controlled trial of its effect on cognitive function.
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FAQ:
What's the MOQ?
1 gram or 1 kilograms according to different products
Can i get free sample first?
Usually we can ship 10~20 grams free sample for your evaluation first and ship by using customer's account.
What's the packaging?
Aluminum foil bag packaging per kg and 25kg per drum
How to control the quality?
Each batch will be passed through strict testing and inspection before shipment, ensure that we'll provide COA for you.
When will you ship the cargo and how many days for delivery?
Usually ship it within 3 working days, and it takes 3~5 days for delivery by DHL;
What's the payment method?
TT ,L/C or Western union, Paypal
