What is Macleaya Cordata Extract?

Macleaya Cordata Extract It is extracted from fruit clip of the wild plant"Macleaya cordata (Willd.) R. Br", also called as "Pink Plumepoppy" in China

English Name: Macleaya cordata extract 
Latin Name: Macleaya cordata (Willd.)
Active Ingredient: Total alkaloids 60%-90% 
Extract Method: Ethanol/Water
CAS No.: 2447-54-3
Molecular Formula: C20H14NO4+
Molecular Mass: 332.33
Description:
Macleaya cordata Extract has the function of detumescence, detoxification and pesticide. It can be used in the treatment of furuncle, abscess, malignant boil, ulcer, scald and intractable tinea, etc. The product is virose and can not be taken orally.
Sanguinarine and chelerythrine containing in the product can restrain the growth of Gram positive bacteria in vitro. They are more sensitive to diplococcus pneumonlae, staphylococcus aureus and bacillus subtilis, and have stronger bacteriostastic activity than berberine. Macleaya Cordata has the function of antieelworm and antileptospira. Animal body experiment taken with rabbit contracting diplococcus pneumonlae proves that the injection of this product can inhibit and postpone the effect of fervescence caused by diplococcus pneumonlae, and have the function of antibiosis and refrigeration. The injection can also be used to treat lobar pneumonia, acute quinsy tonsillitis, tympanitis and tumor of thyroid. etc. The suppositories of sanguinarine and chelerythrine are used on the treatment of cervical erosion in clinically.Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation.
Macleaya cordata contains several alkaloids including sanguinarine, chelerythrine, protopine, and allocryptopine.Our product, Macleaya cordata extract mainly constains with sanguinarine and chelerythrine.It was been show to be reversible inhibitors of the enzymatic hydrolysis of acetylthiocholine.It was reported that a study was made of a possible inhibitory action on the enzymatic hydrolysis of acetylthiocholine by human erythrocyte acetylcholinesterase of principal alkaloids isolated from Chelidonium majus L. and Macleaya cordata and microcarpa,and of drugs Ukrain and Sanguirythrine. Among all examined agents berberine, sanguinarine and Sanguirythrine were the strongest inhibitors of this reaction.Judging from the data obtained, sanguinarine and chelerythrine exert similar inhibitory effects on the reaction of enzymatic hydrolysis of acetylthiocholine.

Function
(1). With the function of insecticide, to some extent, it can effectively inhibit bacteria and fungi;
(2). With the function of detoxifying and eliminating swelling;
(3). With the function of anti-inflammatory, anti-bacterial and antiviral.
Application
Mainly used in pharmaceutical field, treating various inflammatory diseases we can use macleaya intramuscular injection, which gets excellent results.